Economic isolation and characterization of oleanolic acid from Eugenia caryophyllus (Spreng.)

Authors

  • Nilesh Bhimrao Banarase Department of Pharmacognosy & Phytochemistry, Apollo College of Pharmacy, Anjora, Durg, India- 491 001
  • Chanchal Deep Kaur Department of Pharmaceutical Sciences, Shri Rawatpura Sarkar Institute of Pharmacy, Kumhari, Durg, India- 490 042

DOI:

https://doi.org/10.48129/kjs.v48i1.8620

Keywords:

Oleanolic acid, Eugenia caryophyllus (Spreng.), Isolation, Characterization, Purity

Abstract

Oleanolic acid, an interesting molecule found widespread throughout the plant kingdom with promising pharmacological activities. However, the utilization of oleanolic acid in the modern therapy is quite difficult due to lack of proper isolation method and selection of commercially available raw material. In the present study, the new economic method for the isolation of oleanolic acid from Eugenia caryophyllus (Spreng.) commonly known as clove bud was developed. The yield of oleanolic acid was found to be 1.8 g/ 100 g dry matter. The isolated oleanolic acid was characterized by TLC, DSC, FTIR, ESI-HRMS, and NMR studies. The purity of an isolated oleanolic acid was determined by HPLC studies and found to be 97.7% pure. The method so developed is simple, cost-effective with industrial applicability.

Author Biographies

Nilesh Bhimrao Banarase, Department of Pharmacognosy & Phytochemistry, Apollo College of Pharmacy, Anjora, Durg, India- 491 001

Department of Pharmacognosy & Phytochemistry,

Associate Professor & Ph.D. Research Scholar

Chanchal Deep Kaur, Department of Pharmaceutical Sciences, Shri Rawatpura Sarkar Institute of Pharmacy, Kumhari, Durg, India- 490 042

Department of Pharmaceutical Sciences

Professor & Principal

References

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Published

2020-12-23