In vitro Proportional investigation of Different Promoted Pantoprazole Sodium brands of Gastro-Resistant Tablets

Authors

  • Hindustan Abdul Ahad Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, Ananthapuramu – 515721, Andhra Pradesh, India http://orcid.org/0000-0001-5329-6878

DOI:

https://doi.org/10.48129/kjs.v48i1.8598

Keywords:

Pantoprazole, brand, evolution, kinetics.

Abstract

The present work was to a comparative exploration of some physicochemical possessions viz., weight change, thickness, diameter, hardness, disintegration time, in-vitro drug discharge and analyse studies of various commercially available Pantoprazole sodium tablets (PST) of 40 mg. The hardness, loss on friability, dissolution test, disintegration test and uniformity of drug content were evaluated. All the brands meet the requirements as per the pharmacopoeial standards. The dissolution profile study revealed that PST-1 had faster while PST-2 has slower. The dissolution informations were kinetically treated.

Author Biography

Hindustan Abdul Ahad, Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, Ananthapuramu – 515721, Andhra Pradesh, India

Dept, of Industrial Pharmacy, rank-1

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Published

2020-12-23