Eradication of Klebsiella pneumoniae biofilms and persister cells using silver nitrate

persister cells and biofilms in clinical Klebsiella pneumoniae isolates

Authors

  • Sarah Naji Aziz Mustansiriyah University

DOI:

https://doi.org/10.48129/kjs.15153

Abstract

To perceive the relationship between the emergences of antibiotics persistence, biofilm formation, and to study the role of silver nitrate in fighting these microbes, a total 50 clinical Klebsiella pneumonae isolates were collected from clinical sources and identified using genotypic identification by using specific primer (rpoB gene) from housekeeping genes.  Detection of their biofilm-forming abilities were carried out. The eradication effect of silver nitrate to control bacterial persistence and reducing the biofilm-forming abilities were studied. We found that 40 isolate (80%) were biofilm-formers. From Bacterial persisters, (75%) were biofilm-formers. Silver nitrate showed a great role to eradicate persister cells and inhibition of bacterial biofilm formation of clinical isolates of K. pneumoniae.

Published

08-05-2022

Issue

Section

Biology